Composite Physiologic Index, Percent Forced Vital Capacity and Percent Diffusing Capacity for Carbon Monoxide Could Be Predictors of Pirfenidone Tolerability in Patients with Idiopathic Pulmonary Fibrosis
نویسندگان
چکیده
منابع مشابه
The Role of EDD (Exercise Capacity, Dyspnea, and Diffusing Capacity of Lungs for Carbon Monoxide) Index in Pulmonary Fibrosis Secondary to Scleroderma
Introduction: Pulmonary involvement secondary to Systemic Sclerosis (SSc) is the major cause of morbidity and mortality in SSc patients. We designed this study to determine the correlation of important lung function parameters with lung High Resolution CT (HRCT) scan findings. Materials and Methods: Thirty–two consecutive diffuse SSc patients with pulmonary fibrosis were enrolled in this cross...
متن کاملthe role of edd (exercise capacity, dyspnea, and diffusing capacity of lungs for carbon monoxide) index in pulmonary fibrosis secondary to scleroderma
introduction: pulmonary involvement secondary to systemic sclerosis (ssc) is the major cause of morbidity and mortality in ssc patients. we designed this study to determine the correlation of important lung function parameters with lung high resolution ct (hrct) scan findings.materials and methods: thirty–two consecutive diffuse ssc patients with pulmonary fibrosis were enrolled in this cross-s...
متن کاملEffect of hyperlipidaemia on pulmonary diffusing capacity for carbon monoxide.
There is conflicting evidence on the effect of hyperlipidaemia on pulmonary diffusing capacity for carbon monoxide (DLCO or TLCO) in man. We have measured the carbon monoxide transfer factor per unit alveolar volume (TLCO/VA or KCO) by the single breath method in 25 patients with hyperlipidaemia, and in three normal subjects before and after infusions of an intravenous fat emulsion, Intralipid....
متن کامل[The measurement of pulmonary diffusing capacity for carbon monoxide].
The pulmonary diffusing capacity for oxygen (DLo,) is of great physiological and clinical significance (1). Its measurement, however, is relatively complex (2). Pulmonary diffusing capacity for carbon monoxide (DLco) which, it is usually assumed,' can be converted to DL02 from the known solubilities and molecular weights of the two gases, is, in general, more readily measured. Further, since th...
متن کاملPirfenidone should be prescribed for patients with idiopathic pulmonary fibrosis.
Pirfenidone works. There have been four randomised placebo-control trials of pirfenidone for the treatment of idiopathic pulmonary fibrosis (IPF); a phase II and phase III study in Japan, and two international multicentre phase III studies. In all four studies, patients treated with pirfenidone had slower rates of decline in lung volume (vital capacity (VC) in the Japanese studies and forced vi...
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ژورنال
عنوان ژورنال: Internal Medicine
سال: 2015
ISSN: 0918-2918,1349-7235
DOI: 10.2169/internalmedicine.54.4118